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71.
Microinjections of carbachol (carbamylcholine chloride) into the amygdaloid complex of rats produced behavioral and electrophysiological seizures which subsided within 24 hours. A persisting functional change caused a deficit in avoidance learning 1 to 3 weeks after the seizure. A cholinergic system is implicated by the fact that cholinergic blockade (scopolamine) of the amygdala during training reversed the effects of the seizures induced by carbachol. 相似文献
72.
Grossman JN 《Science (New York, N.Y.)》2000,290(5490):283-285
Primitive meteorites provide a glimpse into the early history of our solar system, but some of the most primitive meteorites are also rarely found on Earth. In his Perspective, Grossman explains why the fall of the Tagish Lake meteorite on 18 January 2000 in British Columbia, Canada, was a lucky event for meteorite researchers. The first analysis of the meteorite is reported by Brown et al. Well-preserved organic matter in the meteorite provides a unique opportunity to study the nature and origin of organic matter that may have accreted on early Earth and played a role in the origin of life. 相似文献
73.
The specific respiration rate at 20 degrees C (R(20)) of peach leaves and stems declined rapidly from a high value in the early spring (22.5 nmol CO(2) g(dw) (-1) s(-1)) to relatively constant rates by July (3.1 nmol CO(2) g(dw) (-1) s(-1)). Leaf R(20) declined more rapidly than current-year stem R(20), but leaf and current-year stem R(20)s were similar by July. The R(20) of current-year stems in July was approximately 2.5 times greater than that of one-year-old stems (1.3 nmol CO(2) g(dw) (-1) s(-1)), and about 30 times greater than that of the trunk R(20) (0.1 nmol CO(2) g(dw) (-1) s(-1)). The Q(10)s of leaves and stems were approximately 2 for a temperature increase between 20 and 30. The Q(10)s above 30 were 2.03 for leaves but only 1.61 for stems. Leaves and current-year stems accounted for 2 and 17% of the aboveground vegetative biomass in April and August, respectively, but accounted for 59-80% of total daily (24 h) respiration. Although trunk biomass accounted for 91 and 77% of aboveground vegetative biomass, in April and August, respectively, trunk respiration accounted for only 8-15% of daily aboveground respiration. Before harvest, during a period when fruit growth was source-limited, daily fruit respiration exceeded respiration by all aboveground vegetative organs. 相似文献
74.
Increased planting of hard mast oak species in the Lower Missouri River floodplain is critical as natural regeneration of
oak along the Upper Mississippi and Lower Missouri Rivers has been limited following major flood events in 1993 and 1995.
Traditional planting methods have limited success due to frequent flood events, competition from faster growing vegetation
and white-tailed deer herbivory. Results of early growth response of swamp white oak (Quercus bicolor Willd.) seedlings in relation to initial acorn mass and size, and early rapid shoot growth for seedlings produced by containerized
root production method (RPM™), are presented. Containerized RPM™ seedlings grown in the greenhouse under optimal conditions
demonstrate that seed size had no discernable impact on first-year root or shoot size. Seedling survival for the first two
years and acorn production for the first three years after outplanting are presented, comparing use of containerized RPM™
swamp white oak seedlings to nursery stock. Flood tolerant precocious RPM™ oak seedlings in the floodplain provide a source
of food for acorn-consuming wildlife ten to fifteen years sooner than oaks originating from natural regeneration, direct seeding
or traditional bare root planting. Compared to bare root nursery stock that produced no acorns, some RPM™ swamp white oak
seedlings averaged 4.3, 5.2, and 6.3 acorns/seedling in the first three years after fall outplanting.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
75.
Summary The reasons for the interest in the rheology of wood and the favoured lines of research are stated. The response of wood can often be predicted adequately on the basis of previous studies but notable gaps remain in our knowledge. Future research should avoid going over well trodden ground and should concentrate on filling some of the gaps listed. The factor of greatest importance is the interaction of load with change in moisture content. International cooperation in rheological research on wood would be of great benefit.
Based on a paper contributed to the Fifth International Congress on Rheology, Kyoto, 1968. 相似文献
Zusammenfassung Nach einer Begründung der Wichtigkeit der Rheologieforschung werden die hier verfolgten Einzelfragen kurz erläutert. Durch rheologische Untersuchungen kann zwar das voraussichtliche Verhalten des Holzes meist mit genügender Genauigkeit vorausgesagt werden, aber die Kenntnisse auf diesem Gebiet sind noch lückenhaft. Zu den wichtigsten Zusammenhängen gehört die Kenntnis der Wechselwirkungen zwischen Belastung einerseits und veränderlicher Holzfeuchte andererseits. Engere internationale Zusammenarbeit könnte hier, wie auch in anderen Fragen sehr nutzbringend sein.
Based on a paper contributed to the Fifth International Congress on Rheology, Kyoto, 1968. 相似文献
76.
Effects of FGF10 on Bovine Oocyte Meiosis Progression,Apoptosis, Embryo Development and Relative Abundance of Developmentally Important Genes In Vitro 下载免费PDF全文
RF Pomini Pinto PK Fontes B Loureiro AC Sousa Castilho J Sousa Ticianelli E Montanari Razza RA Satrapa J Buratini C Moraes Barros 《Reproduction in domestic animals》2015,50(1):84-90
Fibroblast growth factor (FGF10) acts at the cumulus oocyte complex, increasing the expression of cumulus cell expansion‐related genes and oocyte competency genes. We tested the hypothesis that addition of FGF10 to the maturation medium improves oocyte maturation, decreases the percentage of apoptotic oocytes and increases development to the blastocyst stage while increasing the relative abundance of developmentally important genes (COX2, CDX2 and PLAC8). In all experiments, oocytes were matured for 22 h in TCM‐199 supplemented with 0, 2.5, 10 or 50 ng/ml FGF10. In Experiment 1, after maturation, oocytes were stained with Hoechst to evaluate meiosis progression (metaphase I, intermediary phases and extrusion of the first polar body) and submitted to the TUNEL assay to evaluate apoptosis. In Experiment 2, oocytes were fertilized and cultured to the blastocyst stage. Blastocysts were frozen for analysis of COX2, CDX2 and PLAC8 relative abundance. In Experiment 1, 2.5 ng/ml FGF10 increased (p < 0.05) the percentage of oocytes with extrusion of the first polar body (35%) compared to 0, 10 and 50 ng/ml FGF10 (21, 14 and 12%, respectively) and FGF10 decreased the percentage of oocytes that were TUNEL positive in all doses studied. In Experiment 2, there was no difference in the percentage of oocytes becoming blastocysts between treatments and control. Real‐time RT‐PCR showed a tendency of 50 ng/ml FGF10 to increase the relative abundance of COX2 and PLAC8 and of 10 ng/ml FGF10 to increase CDX2. In conclusion, the addition of FGF10 to the oocyte maturation medium improves oocyte maturation in vitro, decreases the percentage of apoptotic oocytes and tends to increase the relative abundance of developmentally important genes. 相似文献
77.
Electron microprobe analyses of an extraordinarily large metal grain from the Murchison type 2 carbonaceous chondrite gave 0.24 mole percent silicon. Thermodynamic calculations show that this is a natural consequence of condensation of alloys from the solar nebular gas at a total pressure l0(-5) less, similar P(tot) < l0(-3) atmosphere, provided they failed to equilibrate with it after cooling to < 1200 kelvins. 相似文献
78.
79.
Mitochondrial DNA in yeast and some mammalian species 总被引:19,自引:0,他引:19
Yeast DNA, in a cesium chloride density gradient, shows a minor or satellite band with a density lower than that of the main nuclear component. The DNA isolated from purified mitochondria of yeasts corresponds in density to this satellite band. In solution, this DNA more easily undergoes renaturation as compared to DNA from cell nuclei. The ease of this renaturation is presumably due to a homogeneity greater than that of nuclear DNA. Mitochondrial DNA isolated from several mammalian species has the same or higher density than nuclear DNA, but differs in its ready renaturability. 相似文献
80.
Detecting novel associations in large data sets 总被引:3,自引:0,他引:3
Reshef DN Reshef YA Finucane HK Grossman SR McVean G Turnbaugh PJ Lander ES Mitzenmacher M Sabeti PC 《Science (New York, N.Y.)》2011,334(6062):1518-1524
Identifying interesting relationships between pairs of variables in large data sets is increasingly important. Here, we present a measure of dependence for two-variable relationships: the maximal information coefficient (MIC). MIC captures a wide range of associations both functional and not, and for functional relationships provides a score that roughly equals the coefficient of determination (R(2)) of the data relative to the regression function. MIC belongs to a larger class of maximal information-based nonparametric exploration (MINE) statistics for identifying and classifying relationships. We apply MIC and MINE to data sets in global health, gene expression, major-league baseball, and the human gut microbiota and identify known and novel relationships. 相似文献